تلخیص
Introduction: Tuberculous meningitis is not an uncommon cause of
prolonged morbidity and mortality in our set up.
Objective of the Study: To describe our experiences in the presentation,
diagnostic rigor and outcome of the disease in our setup.
Methods and Material: The record of 100 cases of tuberculous meningitis
admitting from 1st February 2013 to 31st March 2014 in Pediatric unit I,
Bahawal Victoria Hospital Bahawalpur was reviewed.
Result: There were 100 cases, out of which 59% were male. The mean ±
SD age of presentation was 36.91 ± 32.23 months. There were only
children 20% who were above 5 years of age. The contact was positive
in 24% cases. 31% were having BCG scar mark. 94% cases were
admitted in stage III while only 6% in stage II. The mean ± SD duration of
preadmission symptoms was 14.77 ± 6.74 days.
The initial chest radiograph was abnormal in 40% cases. Cranial CT
showed hydrocephalus in 93% and multiple infarctions in 45% cases,
tuberculoma in 2% and basilar enhancement in 95% cases.
The mean ± SD CSF white blood cell count (mm3) at time of
presentation was 246.8 ± 174.2. Predominant cells were lymphocytes in
93% while polymorph nuclear leukocytes in 7% of the cases. The mean ±
SD CSF protein (mg/dl) at time of presentation was 153.53 ± 65.39 and
that of glucose (mg/dl) 31.47 ± 13.11. The case fatality during hospital
stay was 25%.
Conclusion: Tuberculous meningitis is an important childhood illness with
high mortality and morbidity having non specific signs and symptoms.
Shahzadi Asma Tahseen. (2016) Tuberculous Meningitis at Tertiary Care Unit, Pakistan Pediatric Journal, Volume 40, Issue 1.
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