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Chlorfenapyr is a widely used insecticide. Despite its use, human
poisoning data is not sufficient and has been rarely reported.
Chlorfenapyr interferes with oxidative phosphorylation at mitochondrial
level thus depriving the target organism of energy and causing death.
Sign and symptoms include nausea, vomiting, fever and central nervous
system effects with delayed neurotoxicity. It is converted into active
metabolite after some time which may be responsible for delayed
neurological symptoms. This is a case report of accidental poisoning of
Chlorfenapyr in children who presented about ten days after ingestion
with neurological symptoms and white matter changes on MRI.
Sobia Naeem, Prof. Ayesha Arif, Prof. Mahmood Shaukat. (2016) A Case Report of Chlorfenapyr Poisoning , Pakistan Pediatric Journal, Volume 40, Issue 3.
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