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Aims and Objective: The objective of this study was to assess the
effects of Inhaled corticosteroids on growth of asthmatic children.
It was an observational cross sectional study. Two groups were
designed in the study. One is Control group which include normal,
healthy individuals having no clinical findings suggestive of any
endocrinal disorder or any disease that might affect growth and other
group isasthmatic patients who were treated with inhaled
corticosteroids.
Patients and Methods: This is a case control observational study in
which, growth parameters were assessed in asthmatic children taking
inhaled corticosteroids and healthy subjects. Height, weight and
head circumference of all subjects were measured. All collected
information was entered in to SPSS version 20.0 and analysed through
its statistical package.
Results: Mean height and head circumference was the same in
asthmatic patient as compared to healthy subjects. There was no
effect of doses and duration of ICS therapy on patient’s height and
head circumference. Weight was significantly lower in asthmatic
patients than control. However, different doses and duration of ICS
therapy has no effect on patient’s weight.
Conclusion: We concluded that although there was no effect of dose
and duration of ICS on any growth parameter but there were
significant reduction in weight of asthmatic children on ICS therapy
than control group. However, Asthma, poverty or malnourishment
may also be responsible for difference in weight between these two
groups.
Farhana Shahzad, Iqbal Bano, Bushra Mubarik, Prof Ahsan Waheed Rathore, Saba Aziz. (2016) Effect of Inhaled Corticosteroids on Growth of Asthmatic Children , Pakistan Pediatric Journal, Volume 40, Issue 3.
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