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Pakistan Pediatric Journal is being published on regular basis since 1977 under the auspices of PPA. PPA is grateful and appreciate the services of Prof. S M K Wasti (late) and Prof. S M Haneef for ... Read More

Infantile colic is a self-limited condition that deserves treatment because itcould represent an early traumatic insultfor the intestine and could be theearly expression of atopic disease, gastroi ... Read More

Exogenous lipoid pneumonia is an uncommon condition resulting from aspiration or inhalation of fat like material, such as mineral oil found in laxatives and various aerosolized industrial materials. W ... Read More

Gastroschisis is a congenital abdominal wall defect. It involves all the layers of abdominal wall. There is no covering membrane and usually the defect is on the right side of the umbilicus. Prognosis ... Read More

The World Health Organization (WHO) defines adolescents as the age group 10–19. Adolescents constitute 18-25% of the population in member countries of South East Asia Region. Reproductive health issue ... Read More

Objective: The objective of the study was to determine the sensitivity of Pakistan Pediatric association scoring chart system as a diagnostic tool for childhood tuberculosis (PPASCFSCTB) in the admitt ... Read More

Objective: A case-control clinical trial was conducted to determine the association of iron deficiency and first febrile seizure in children of aged 6 – 60 months. Methods: Hematological parameters f ... Read More

Aim and Objective: To determine the frequency of various causes of pleural effusion in children. To evaluate the treatment options in these cases. Patients and Methods: It is a case series study done ... Read More

Objective: To determine the pattern different neuronal migrational disorders (NMDs) and their association of other neurological conditions. Patients and Methods: This is a retrospective analysis of t ... Read More

Objective: To identify possible risk factors for the development of Vitamin D deficiency rickets in children under 5 years of age. Methods: This case – control study was conducted in the Department o ... Read More

Objective: to find frequency of low birth weight (LBW) and maternal factors associated with it. Place of Study Department of Obstetrics and Gynaecology, Sir Syed Hospital (Private Teaching Hospital) ... Read More

Necrotising Enterocolitis (NEC) is the most common gastrointestinal emergency in preterm neonates and a major cause of morbidity and mortality in the developed world. Aga Khan University Hospital in K ... Read More

In September 2000 Pakistan signed the Millennium Declaration, but it is “off track” concerning the targets to be achieved for meeting the UN’s 8 Millennium Development Goals (MGDs), and is unlikel ... Read More

www.pakpedsjournal.org.pk/www.ppa.org.pk Vol. 36(2) June, 2012 ISSN 0304 4904 PAKISTAN PAEDIATRIC JOURNAL A JOURNAL OF PAKISTAN PAEDIATRIC ASSOCIATION Indexed in EMBASE/Excerpta Medica & Index m ... Read More

Background: Most acute wheezing episodes in preschool children are associated with rhinovirus. Rhinovirus decreases extracellular adenosine triphosphate levels, leading to airway surface liquid de ... Read More

Congenital dyserythropoietic anaemias (CDA) are a group of rare hereditary disorders characterized by ineffective erythropoiesis and dyserythropoieses. Three forms of CDA have been characterized type- ... Read More

Menkes disease (MD) is a rare X-linked neurodegenerative disorder. It is caused by a mutation in the ATPTA gene, which codes for the copper transporting ATPase in the cell organelles. We report a boy ... Read More

Mutation in genes encoding for proteins involved in glycogen synthesis, degradation or regulation results in various inborn errors of glycogen metabolism. The disorders that result in abnormal storage ... Read More

Background: This study was performed to evaluate the postoperative problems and quality of life of children who survived after repair of esophageal atresia with distal tracheoesophageal fistula. Meth ... Read More

Objective: To study the outcome of open reduction and fixation with K-wires of fractures of lateral condyle of humerus in children presenting between 3 – 12 weeks after injury. Methodology: This was ... Read More

Aim: To evaluate the normal diameter of portal vein and its physiological Doppler ultrasound flow characteristics in children. Materials and Methods: Children (0-18years old) with no clinical evidenc ... Read More

Objective: To know the clinical manifestations of enteric fever on the basis of age difference in <5 years and ≥ 5 years old children. Methods: This study was conducted to know the clinical profile o ... Read More

Dengue hemorrhagic fever (DHF) is a serious form of dengue virus infection. Third space fluid leak is characteristic of DHF. Prognosis depends upon early detection, meticulous monitoring and judicious ... Read More

Background: Bacterial meningitis causes wide spectrum of acute complications leading to childhood morbidity and mortality. Objective: This study was conducted to obtain data regarding the frequency o ... Read More

Background: Diarrhoea is the second leading cause of childhood mortality in children under five years of age. Group A rotavirus is known to be the leading cause of severe diarrhoeal diseases and dehyd ... Read More

Objective: To determine the clinical efficacy of probiotics Saccharomyces boulardii” in children admitted with acute watery diarrhoea Design: Randomized controlled trial Setting and Duration: Depart ... Read More

The past few decades have seen a noticeable increase in the number of scientific publication, especially in the field of biomedical science. “A primary contributor to this increase in academic activit ... Read More

Unfortunately, diarrhea maintains leadership role in mortality and morbidity of Pakistani children despite decades of concerted efforts and special programs. There is some positive news over past dec ... Read More

Objective: To evaluate the effect of domperidone use on corrected QT interval in premature infants. Study Design: A prospective study of premature infants receiving domperidone was included in th ... Read More

Joubert syndrome (JS) is a rare disorder characterized by hypotonia, ataxia, abnormal eye movements, abnormal respiratory pattern, developmental delay and molar tooth sign on magnetic resonance imagin ... Read More

Acute hepatitis E is commonly seen in countries with hot climate, poor sanitation and unhygienic water supplies. Anemia is one of the complications of acute viral hepatitis. The present study reports ... Read More

Polyneuropathy in childhood can be of varied etiology, the commonest being Guillain-Barré syndrome (GBS). However, Diphtheritic neuropathy should be considered in differential diagnosis because in our ... Read More

Introduction: There are reports that there is high prevalence of H pylori infection in patients and diabetes mellitus. Objective: To evaluate helicobacter pylori infection in cases of diabetes mellit ... Read More

Objective: To study the association maternal mid-upper arm circumference and birth of low birth weight babies. Methods: It is a hospital-based case control study conducted at the Neonatal Unit of Dep ... Read More

Ventilation Associated Pneumonia (VAP) is one of the important causes of weaning failure from mechanical ventilation. Appropriate treatment of VAP according to culture and sensitivity pattern leads to ... Read More

Objective: To determine the types of infections in primary nephrotic syndrome. Study Design: Descriptive study. Place and Duration of Study: Paediatric departments of Shaheed Mohtrama Benazir Bhutto ... Read More

Introduction: Enteric fever is a systemic infection caused by the bacteria, Salmonella enterica serovara Typhi (S.typhi) and Salmonella enterica serovara Paratyphi (S. paratyphi A, B and C). Disease b ... Read More

Objective: To compare the effectiveness of intramuscular artemether with intravenous quinine sulphate infusion in cases of cerebral malaria. Study Design: Randomized clinical trial. Setting: Pediatr ... Read More

Objective: The objective of the study was to determine the frequency of malaria in febrile children aged 2 months to 5 years and to document type of plasmodium species in the area. Methodology: Malar ... Read More

Birth asphyxia is one of the leading causes of neonatal mortality and morbidity in Pakistan. Large proportions of survivors go on to develop cerebral palsy contributing to the largest group of intelle ... Read More

Malaria is the second most prevalent and devastating disease in the country. Approximately 60 percent of the population is living in areas where the disease is endemic. Approximately 4.5 million proba ... Read More

Pakistan Paediatric Journal Annual Index – 2011 Subject-wise ... Read More

Pakistan Paediatric Journal, Annual Index – 2011, Author-wise ... Read More

Expanded Program on Immunization and its Deterioration in Pakistan Expanded Program on Immunization (EPI) was launched in Pakistan on countrywide basis in 1978. It aims at protecting children by i ... Read More

NEWS AND VIEWS ... Read More

Metatropic Dysplasia is a rare spondylometaphyseal dysplasia with characteristic radiologic findings. We report two sisters presenting with short stature, varus and valgus deformities of their lower l ... Read More

Case history of young couple who came for antenatal advice with their two children who were developmentally delayed, having hand flapping, frequent paroxysms of laughter and puppet like gait, these un ... Read More

Chediak Higasi syndrome (CHS) is an autosomal recessive disorder characterized by partial occulocutaneous albinism, increased susceptibility to infection, photophobia, a mild bleeding diathesis and a ... Read More

Rosai-Dorfman disease is an idiopathic histiocytic proliferative disorder characterized by sinus histiocytosis and massive lymphadenopathy. Extranodal involvement has also been reported. We report the ... Read More

Objectives: The objective of the study is to evaluate gastrointestinal problems in cancer patients during treatment. Patients and methods: In a sample of 150 children having different childhood malig ... Read More

The ultrasonic scalpel (US) has been used in tonsil surgery for several years. The comparison of ultrasonic scalpel tonsillectomy with other tonsillectomy techniques has been the subject of many studi ... Read More

Objective: Transfusion transmitted viral infections are more frequent in developing countries like Pakistan due to lack of facilities for proper donor screening against these viruses. This study was c ... Read More

Objective: To evaluate the effectiveness and safety of Cyclosporine-A as the mainstay of treatment for induction of complete and sustained remission in steroid resistant nephrotic syndrome in children ... Read More

Objective of study: To see epidemiology, clinical presentation and outcome of tetanus in children beyond neonatal age. Study Design: Retrospective descriptive. Place and duration of study: This stud ... Read More

Objective: To compare the efficacy of hypo-osmolar versus WHO-ORS solution in children with acute watery diarrhea (AWD). Methods: A double blind, randomized controlled trial was conducted in the depa ... Read More

The Expanded programme on Immunization (EPI) was established by the World Health Organization in 1974 to ensure universal access to routine immunizations in children. Six diseases were targeted at: Tu ... Read More