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Introduction: Urinary tract infection is one of the most common infections
encountered in childhood. Although the organisms causing these
infections remain same but their sensitivity and resistance patterens
keeps on changing frequently so their periodic surveillance is necessary
to treat UTI and prevent its complications. This study was conducted to
determine the sensitivity pattens of these uropathogens in children at
Fauji Foundation Hospital Rawalpindi Pakistan.
Materials and Methods: This is a retrospective descriptive analysis of 193
patients aged 2mnothsto 12 years with culture confirmed UTI . The study
was conducted over a period of 1 year and included data of patients
with culture positive UTI both from in and outpatient settings of pediatric
department, Fauji Foundation Hospital Rawalpindi.
Results: Total 193 patients have cuture positive UTI. Out of these males
were 41% and females were 59%. There was male predominance in
children less than 1 year of age and thereafter ratio reverses. Most
common organism grown on culture was Ecoli 38% followed by
klebsiella13% and pseudomonas 12.5%. Regarding overall drug sensitivity
patterns imipenim/meropenim showed the highest sensitivity of 74.3%
followed by amikacin71%, ciprofloxacin 56.5% and nitrofurantoin 48%.3rd
generation cephalosporins, co-trimoxazole and ampicillin showed the
least sensitivities. Ampicillin showed the highest resistance of 91%. E coli
showed 100% sensitivity to imipenim/meropenim.
Conclusion: The sensitivity and resistance patterns of uropathogens to
commonly used antibiotics which were used previously for treating UTI is
changing. This must be taken into consideration before selecting
empirical treatment for children with UTI
Sumaira Khalil, KiranMushtaqToor, HumaSaleem Khan. (2016) Etiological Profile and Sensitivity Pattern of Uropathogens in Children , Pakistan Pediatric Journal, Volume 40, Issue 2.
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