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Objective: The purpose of this study was to determine the prevalence and risk factors of newborn jaundice.
Study Design: In this retrospective study, 3200 newborns with jaundice with bilirubin level >17 mg/dl were investigated.
Place and Duration of Study: The newborn department of Ghaem Hospital of Mashhad, Iran during 2007-2017.
Material and Methods: A self-administered questionnaire containing maternal information, neonatal profileand laboratory parameters was completed.
Results: From the 14183 neonates referred to the study center over 10 years, 3200 were hospitalized for jaundice. The most common underlying diagnoses were: idiopathic (n=1754, 66.9%), ABO incompatibility (n=279,10.6%), G6PD deficiency (n=149, 6.0%), urinary tract infection (n=101, 3.9%), Rh incompatibility (n=80, 3.1%), sepsis (n=44,1.7%), polycythemia (n=44, 1.7%). The presence of pregnancy complications (25%), history of jaundice in a previous sibling (42.9%) and history of hospitalization (32.4%) were other predisposing factors in newborns admitted with jaundice.
Conclusion: The major known causes of newborn jaundice were ABO incompatibility, G6PD deficiency, urinary tract infection, Rh incompatibility, polycythemia and hypothyroidism.
HASSAN BOSKABADI, MARYAM ZAKERIHAMIDI, EZZAT KHODASHENAS. (2020) A Study of Epidemiology and Predisposing Factors of Newborn Jaundice in 3200 Infants, Pakistan Pediatric Journal, Volume 44, issue 4.
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