جلد
شمارہ
مقالے کی قسم
زبان
تاریخِ موصولہ
تاریخِ قبولیت


تلخیص
Objective: To compare mean change in terms of respiratory rate, oxygen saturation and Respiratory Distress Assessment Index (RDAI) score of nebulized epinephrine with intravenous dexamethasone versus nebulized salbutamol in infants hospitalized with acute bronchiolitis. Study Design: Randomized Controlled Trial Place and Duration of Study: Pediatric Unit of Khyber Teaching Hospital from 15-10-2016 to 15-042017. Material and Methods: using non-probability consecutive sampling technique and inclusion criteria 322 patients were included in the study, 166 in group A (nebulized epinephrine with intravenous dexamethasone) and 166 in group B (nebulized salbutamol). SPSS (version 17) was used to enter and analyze the data. A comparison was made in the mean change between the two groups with respect to RDAI, respiratory rate and oxygen saturation at 240 minutes from baseline. Results: Mean age was 5.30 ± 2.89 in group A and 5.25 ± 3.18 in group B. Male made 68% in group A and 78% in group B. Mean change in RDAI score for group A was 1.86±0.58 and for group B 1.04 ± 0.48 (p-value 0.002). There were no differences in the mean change of oxygen saturation or respiratory rate in both groups (p >0.05). Conclusion: Combination therapy of epinephrine with dexamethasone had a more significant response in the clinical score only, and RDAI score was found to be more representative of clinical improvement of patients admitted with acute bronchiolitis

SAMINA SHAMS, SAHAR IQBAL, FARIDA SHERAZI, Bawar Shah. (2021) Comparison of Nebulized Epinephrine with Intravenous Dexamethasone versus Nebulized Salbutamol in Infants Hospitalized With Acute Bronchiolitis, Pakistan Pediatric Journal, Volume 45, Issue 2.
  • Views 260
  • Downloads 19