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Objective: To determine the spectrum of microorganisms causing colonization of central venous catheter in pediatric ICU. Study Design: Cross-sectional study. Place and Duration of Study: Department of Pediatric ICU, the Children’s Hospital & the Institute of Child Health, Lahore, from July 2018 to February 2020. Material and Methods: 203 male and female children from 1 month to 15 years of age with a central venous catheter (CVC) during admission at the PICU were included. Specimens were taken from tip of catheter and sent to laboratory in a sterile container to identify the presence of microorganisms . Results: Of the 203 pediatric patients included, 123 (60.6%) were male and 80 (39.4%) were female with mean age of 5.65±1.374 years. Male to female ratio was 1:1.5 and age range was from 2-11 years. Organisms were identified in 88 patients (43.3%).Out of 88 cases positive cases, 22 (25%) had gram positive, 60 (68.2%) had gram negative and 6 (6.8%) had fungi isolated after culture. Klebsiella (30.7%) was the most common organism followed by Acinetobacter (21.6%) and Coagulase negative Staphylococci (17%). Conclusion: The prevalence of microbial colonization of CVCs is significant, 43.3% in our PICU. Gram negative (68.2%) organisms are commonly isolated from CVCs, Klebsiella (30.7%) being the most prevalent.

AFTAB ANWAR, SHUJA UR REHMAN, AMNA NAZAR, Saed Aftab Ahmad. (2021) Spectrum of Microorganisms Causing Colonization of Central Venous Catheter in Pediatric ICU, Pakistan Pediatric Journal, Volume 45, Issue 1.
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