Abstract
Objective: To investigate the clinical outcome of children with suspected pelvi-ureteric junction obstruction (PUJO) following radioisotope scan.
Study Design: Retrospective study on clinical data of children who underwent DTPA/MAG3 imaging in a tertiary hospital.
Place and Duration of the Study: Department of Nuclear Medicine, Hospital Universiti Sains Malaysia from the year 2008 to 2018.
Material and Methods: The clinical records of these patients were reviewed who were refereed from 2 major tertiary centres. Data was collected using standardized proforma that included age, gender, baseline ultrasound findings, and clinical presentations prior to the imaging. Diagnosis at referral point and actual findings of radionuclide scan were also recorded. Children under 18 who underwent radioisotope imaging (MAG3 and DTPA) were included.
Results: A total 151 patients were recruited into the study. Majority were male [101 (66.9%)]. The median age was four year when the diagnosis was made. The commonest clinical presentations that warranted radionuclide scan were antenatal hydronephrosis and abdominal pain. PUJO was found in 57 (37.7%) patients with 31 (53.1%) of them having left sided obstruction. Pyeloplasty was performed in seventy percent of them, however, 7 (21%) patients showed persistent obstruction during follow up imaging despite the surgical intervention.
Conclusion: There were significant residual hydronephrosis and obstruction despite corrective pyeloplasty, and the need for an imperative measure to prevent future risk of chronic kidney disease in this group of children.
NUR ATIQAH ABDUL RAHMAN, SALMI ABDUL RAZAK, WAN FATIHAH WAN SOHAIMI, Fahisham Taib, Mohd Rizal Mohd Zain, Mohamad Ikram Ilias. (2021) Renal Outcome in Children with Pelviureteric Junction Obstruction (PUJO): A Tertiary Centre Experience, Pakistan Pediatric Journal, Volume 45, Issue 3.
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